3M™ Emphaze™ AEX Hybrid Purifier
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Details
Highlights
- High performance clarification- >4 log DNA reduction, consistent output turbidity (<5 NTU) and Nominal 30% HCP
- Enables higher Protein A column performance over traditional depth filtration
- Significant reduction in filter surface area for sterilizing filters
- >10x less contaminants entering downstream AEX column
- Simplify the process by removing multiple types of impurities in a single process step, leading to better process economics
The 3M Emphaze AEX Hybrid Purifier is a synthetic, multi-mechanism single-use purifier used for biopharmaceutical clarification. It delivers consistent, high purity clarified process fluid by removing soluble and insoluble impurities, such as DNA, HCP, and cell debris, through a combination of chromatographic and size exclusion mechanisms.
Specifications
| Applications | Cell Culture Clarification, Chromatography and Column Protection, Bioburden Reduction, DNA Removal, Adsorptive Depth Filtration |
| Autoclavable | Yes |
| Brands | Emphaze™ |
| Capsule Material | Glass Filled Polypropylene, Polypropylene, Thermoplastic Elastomer (TPE), Glass Filled Polypropylene Oxide, Silicone, Polystyrene, Fluorocarbon, Polysulfone |
| Dimensions (metric) | 4.5 cm x 7.7 cm, 8.8 cm x 7.7 cm, 20.3 cm x 45.2 cm, 10.3 cm x 21.6 cm, 15.2 cm x 21.6 cm, 5.7 cm x 45.2 cm |
| Effective Filtration Area (metric) | 0.23 cm², 1 cm², 1.6 cm², 4 m², 25 m², 170 cm², 340 cm², 1020 cm² |
| End Modification | 3/4 in Sanitary Connectors, 1 1/2 in Sanitary Connectors, Luer Loc |
| Factory Integrity Tested | Capsule Leak Test |
| Fill Volume | 0.55 mL, 1.4 mL, 2 mL, 3.4 mL, 5.5 L, 10.6 L, 13 L, 16 L |
| Filter Material | Functional Non-woven |
| Filter Technology | Anion exchange chromatography |
| Filter Type | Single Use |
| Flow Rate (metric) | 0.4 Millilitre per Minute, 1.4 Millilitre per Minute, 8 Millilitre per Minute, 50 Millilitre per Minute, 100 Millilitre per Minute, 300 Millilitre per Minute, 680 Millilitre per Minute, 4700 Millilitre per Minute |
| Gamma Compatible | No |
| Gamma Sterilized | No |
| Gasket/O-ring Material | Silicone, Fluorocarbon |
| Industries | Life Sciences |
| Inlet Outlet Size | 1.5", 3/4" |
| Inlet/Outlet Connections | 3/4 in Sanitary Connectors, 1 1/2 in Sanitary Connectors, Luer Loc |
| Maximum Operating Pressure (Metric) | 2.4 bar, 2.8 bar, 3.1 bar, 3.4 bar |
| Maximum Operating Temperature (Celsius) | 40 ℃ |
| Membrane Type | Polyamide |
| Micron Rating | 0.2 μm |
| Net Weight (Metric) | 1 g, 1.1 g, 1.6 g, 3.4 g, 9 kg, 9.5 kg, 14.5 kg, 71 kg, 77 kg |
| Product Series | AEX |
| Series | Emphaze™ AEX Series, Emphaze™ AEX |
| Shelf Life | 2 Year |
| Storage Temperature (Celsius) | 0 °C - 30 °C |
| Temperature Range (Celsius) | 0 °C - 40 °C |
| Units per Case | 1.0, 2.0, 4.0 |
| Overall Diameter (Metric) | 4.3 cm, 7.7 cm, 21.6 cm, 45.2 cm |
| Overall Height (Metric) | 4.5 cm, 4.8 cm, 5.7 cm, 5.9 cm, 8.8 cm, 10.3 cm, 15.2 cm, 20.3 cm |
